N-Acetylneuraminic acid (NANA) / Sialic acid

Product name: N-Acetylneuraminic acid(NANA)
Other name: Sialic acid(SA)
CAS No.:131-48-6
Molecular Formula: C11H19NO9
Molecular Weight: 309.27

Sialic acids refer to a family of neuraminic acids which contain nine-carbon acidic amino monosaccharides. The most important member of the sialic acid is N-Acetylneuraminic acid (NeuAc or NANA), occurring most abundantly in glycoproteins and glycolipids. Among all types of sialic acids, only N-Acetylneuraminic acid can be found in human tissues. Therefore, sialic acid, to human beings, refer to NANA. SA manufacture will be carried out using biocatalytic process. The micro-organism cells catalyse two substrates N-acetylglucosamine and pyruvate to biosynthesize SA in a water solution, which is subsequently concentrated and crystalysed. SA will be recrystalised as the refinery process.

Function
Naturally widespread carbohydrate with numerous biological functions, including blood protein half-life regulation, variety of toxin neutralization, cellular adhesion and glycoprotein lytic protection. Starting reagent of biochemical derivatives for the synthesis pharmaceuticals.

1. Anti-virus function
2. Anti-cancer function
3. Anti-inflammation function
4. Defensive function against bacteriological infection
5. Controlling ability of immune system
6. Restraining ability against pigmentation
7. Signal transformation in nerve cell
8. Play a key role in brain development and learning

Application
NANA has been proved to have numerous biological functions, including blood protein half-life regulation, variety of toxin neutralization, cellular adhesion, glycoprotein lytic protection, antioxidisation, brain development, and also starting reagent of biochemical derivatives for pharmaceuticals.

1. used for food and drug in brain development
2. used in nutrition supplement for anti-oxidation & Anti-infection
3. used in daily food to be additives
4. used in cosmetic support